How High-Concentration Cultures Will Characterize the Factory of the Future

نویسنده

  • Jerry Shevitz
چکیده

T oday’s renewed interest in perfusion culture is due to an increased awareness of its advantages, some general improvement in equipment reliability, and a broadening of operational skills in the biomanufacturing industry. Some misperceptions persist, however, according to a 2011 review by Eric Langer (1). Our view here of the history of perfusion and fed-batch processes includes some discussion of technological process improvements and challenges that the bioprocess industry faces. A team of authors at Serono in Switzerland wrote in 2003:

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The Future of Healthcare Facilities: How Technology and Medical Advances May Shape Hospitals of the Future

In this review article, we aim to depict how healthcare facilities may look in the near future from an architectural design point of view. For this purpose, we review newly introduced technology and medical advances in the field of healthcare, such as artificial intelligence (AI), robotic surgery, 3D printing, and information technology (IT), and suggest how those advances may affect the archit...

متن کامل

Risk Assessment of Occupational Exposure to Cement Respirable Particles and Crystalline Silica in a Cement Factory

Introduction: Cement factory workers exposure to airborne particles containing crystalline silica in Portland cement chemical compound can caused pulmonary diseases, including silicosis and lung cancer. The aim of this study was to assess the risk of occupational exposure to respirable cement dust and crystalline silica in a cement factory in Khorasan Razavi province. Methods: In this cross-se...

متن کامل

The Role of Employee Whistleblowing and Raising Concerns in an Organizational Learning Culture – Elusive and Laudable?; Comment on “Cultures of Silence and Cultures of Voice: The Role of Whistleblowing in Healthcare Organisations”

It is inevitable that healthcare workers throughout their careers will witness actual or potential threats to patient safety in the course of their work. Some of these threats will result in serious harm occurring to others, whilst at other times such threats will result in minimal harm, or a ‘near miss’ where harm is avoided at the last minute. Despite organizations encouraging employees to ‘s...

متن کامل

Dynamic modeling to determine production strategies in order to maximize net present worth in small and medium size companies

Determining production rate considering costs and revenues in order to maximize profit is one of the applied problems in small and medium size factories. Mostly existing models in production planning consider production system statically and specify production rate, although the factors determining production rate include many different changes in practice. In fact, by increasing the production...

متن کامل

Modeling Current and Future Potential Distributions of Caspian Pond Turtle (Mauremys caspica) under Climate Change Scenarios

Although turtles are the most threatened taxonomic group within the reptile class, we have a very limited understanding of how turtles respond to climate change. Here, we evaluated the effects of climate changes on the geographical distribution of Caspian pond turtle (Mauremys caspica). We used an ensemble approach by combining six species distribution models including artificial neural network...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2011